Outcomes in acute Charcot neuroarthropathy - a single centre experience over 5 years

C. Stark, T. Murray, C. Gooday, K. Dhatariya, D.T. Loveday

Introduction: The aim of this project was to look at time taken to achieve clinical resolution of diabetic charcot neuroarthropathy (CN) and to see if there was a correlation with location within the foot and overall outcomes.

Methods: A retrospective analysis of newly presenting acute CN patients between 2007 & 2012 was performed. Clinic records were examined to determine the site of the CN; total time treated in a TCC or other removable offloading devices; the presence of co-morbidities.

Results: Fifty CN cases presented during this time. The mean age was 62.5±11.7 (SD) years. Eleven patients had type 1 diabetes mellitus (T1DM). The mean duration of diabetes was 29.7±12.9 years for T1DM, and 14.4±10.7 years for type 2 diabetics. All had palpable foot pulses & peripheral neuropathy at diagnosis. 82% had retinopathy; 34% had CKD stage 3-4. For the 42 patients who completed treatment, the mean duration was 53.9±28.0 weeks, of which a mean of 30.2±25.0 weeks was spent in a TCC. 23.7±16.2 weeks were spent in other offloading devices. Mean duration of treatment for forefoot, mid-foot & hind-foot was 47.2±22.6, 55.9±30.6 & 51.8±23.1 weeks respectively. Thirty-six patients were treated with TCC & other removable offloading devices, 6 were treated with one modality. Fourteen of the 36 (38.9%) required re-casting. Eight patients did not complete treatment: 4 underwent below knee amputation, 2 died, 2 were still undergoing treatment.

Conclusions: In our cohort the mean length of treatment is dependent on the position of the CN. The mean time to resolution is just over 1 year. However, a high percentage (38.9%) deteriorated after coming out of a TCC. This study highlights the need to develop more precise measures to help manage acute CN.